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FORMATE-TETRAHYDROFOLATE LIGASE
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DeCS
Descriptor
English
:
Formate-Tetrahydrofolate Ligase
Descriptor
Spanish
:
Formato-Tetrahidrofolato Ligasa
Descriptor
Portuguese
:
Formato-Tetraidrofolato Ligase
Synonyms
English
:
Tetrahydrofolate Formylase
Tree Number:
D08.811.464.259.550
Definition
English
:
A carbon-nitrogen ligase that catalyzes the formation of 10-formyltetrahydrofolate from formate and TETRAHYDROFOLATE in the presence of ATP. In higher eukaryotes the enzyme also contains METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NADP+) and
METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE
activity.
See Related
English
:
Methenyltetrahydrofolate Cyclohydrolase
Methylenetetrahydrofolate Dehydrogenase (NADP)
History Note
English
:
98(75)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
5709
Unique Identifier:
D005574
Occurrence in VHL
:
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